Based on the sperm analysis, in addition to assessing the count, volume, motility, and morphology of the sperm, we can also evaluate the degree of their DNA damage (fragmentation). This is a distinct, independent parameter for assessing sperm quality. DNA damage in sperm is a very common cause of male infertility.
We examine the DNA of the sperm using a specialized test called Halosperm G2. During this examination, using special solutions, the ratio of sperm with intact DNA to fragmented DNA is determined. By comparing these two values, we obtain the percentage of damaged cells – the DNA fragmentation index (DFI).
This examination is especially important in cases of unexplained infertility or repeated miscarriages. An advantage is that both the sperm analysis and the fragmented DNA sperm examination can be conducted using just one collected semen sample.
